Pathways to a Cure: The CAA Newsletter - Full Archive

Full List of Original Articles

  • Xiong L, Davidsdottir S, Reijmer YD, Shoamanesh A, Roongpiboonsopit D, Thanprasertsuk S, Martinez-Ramirez S, Charidimou A, Ayres AM, Fotiadis P, Gurol E, Blacker DL, Greenberg SM, Viswanathan A. Cognitive Profile and its Association with Neuroimaging Markers of Non-Demented Cerebral Amyloid Angiopathy Patients in a Stroke Unit. J Alzheimers Dis. 2016 Mar 8;52(1):171-8. [Abstract]
  • Fotiadis P, van Rooden S, van der Grond J, Schultz A, Martinez-Ramirez S, Auriel E, Reijmer Y, van Opstal AM, Ayres A, Schwab KM, Alzheimer's Disease Neuroimaging Initiative Adni, Hedden T, Rosand J, Viswanathan A, Wermer M, Terwindt GM, Sperling RA, Polimeni JR, Johnson KA, van Buchem MA, Greenberg SM, Gurol ME. Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study. Lancet Neurol. 2016 Jul;15(8):811-9. [Abstract] [Full Article]
  • Boulouis G, van Etten ES, Charidimou A, Auriel E, Morotti A, Pasi M, Haley KE, Brouwers HB, Ayres AM, Vashkevich A, Jessel MJ, Schwab KM, Viswanathan A, Greenberg SM, Rosand J, Goldstein JN, Gurol ME. Association of Key Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease With Hematoma Volume and Expansion in Patients With Lobar and Deep Intracerebral Hemorrhage. JAMA Neurol. 2016 Dec 1;73(12):1440-1447. [Abstract]
  • Gurol ME, Becker JA, Fotiadis P, Riley G, Schwab K, Johnson KA, Greenberg SM. Florbetapir-PET to diagnose cerebral amyloid angiopathy: A prospective study. Neurology. 2016 Nov 8;87(19):2043-2049. [Abstract] [Full Article]
  • van Veluw SJ, Charidimou A, van der Kouwe AJ, Lauer A, Reijmer YD, Costantino I, Gurol ME, Biessels GJ, Frosch MP, Viswanathan A, Greenberg SM. Microbleed and microinfarct detection in amyloid angiopathy: a high-resolution MRI-histopathology study. Brain. 2016 Dec;139(Pt 12):3151-3162. [Abstract]
  • Lauer A, van Veluw SJ, William CM, Charidimou A, Roongpiboonsopit D, Vashkevich A, Ayres A, Martinez-Ramirez S, Gurol EM, Biessels GJ, Frosch M, Greenberg SM, Viswanathan A. Microbleeds on MRI are associated with microinfarcts on autopsy in cerebral amyloid angiopathy. Neurology. 2016 Oct 4;87(14):1488-1492. [Abstract] [Full Article]
  • Sellal F, Wallon D, Martinez-Almoyna L, Marelli C, Dhar A, Oesterl H, Rovelet-Lecrux A, Rousseau S, Kourkoulis CE, Rosand J, DiPucchio ZY, Frosch M, Gombert C, Audoin B, Min M, Riant F, Frebourg T, Hannequin D, Campion D, Greenberg SM, Tournier-Lasserve E, Nicolas G. APP Mutations in Cerebral Amyloid Angiopathy with or without Cortical Calcifications: Report of Three Families and a Literature Review. J Alzheimers Dis. 2017;56(1):37-46. [Abstract]
  • Boulouis G, Charidimou A, Jessel MJ, Xiong L, Roongpiboonsopit D, Fotiadis P, Pasi M, Ayres A, Merrill ME, Schwab KM, Rosand J, Gurol ME, Greenberg SM, Viswanathan A. Small vessel disease burden in cerebral amyloid angiopathy without symptomatic hemorrhage. Neurology. 2017 Jan 27. [Epub ahead of print] [Abstract]
  • van Veluw SJ, Kuijf HJ, Charidimou A, Viswanathan A, Biessels GJ, Rozemuller AJ, Frosch MP, Greenberg SM. Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy. Acta Neuropathol. 2016 Oct 22. [Epub ahead of print] [Abstract]
  • van Rooden S, van Opstal AM, Labadie G, Terwindt GM, Wermer MJ, Webb AG, Middelkoop HA, Greenberg SM, van der Grond J, van Buchem MA. Early Magnetic Resonance Imaging and Cognitive Markers of Hereditary Cerebral Amyloid Angiopathy. Stroke. 2016 Dec;47(12):3041-3044. [Abstract] [Full Article]
  • van Opstal AM, van Rooden S, van Harten T, Ghariq E, Labadie G, Fotiadis P, Gurol ME, Terwindt GM, Wermer MJ, van Buchem MA, Greenberg SM, van der Grond J. Cerebrovascular function in presymptomatic and symptomatic individuals with hereditary cerebral amyloid angiopathy: a case-control study. Lancet Neurol. 2017 Feb;16(2):115-122. [Abstract]
  • Akoudad S, Gurol ME, Fotiadis P, Koudstaal PJ, Hofman A, Ikram MA, Greenberg SM, Vernooij MW. Cerebral Microbleeds and Cerebrovascular Reactivity in the General Population: The EDAN Study. J Alzheimers Dis. 2016 May 4;53(2):497-503. [Abstract]
  • Charidimou A, Boulouis G, Haley K, Auriel E, van Etten ES, Fotiadis P, Reijmer Y, Ayres A, Vashkevich A, Dipucchio ZY, Schwab KM, Martinez-Ramirez S, Rosand J, Viswanathan A, Greenberg SM, Gurol ME. White matter hyperintensity patterns in cerebral amyloid angiopathy and hypertensive arteriopathy. Neurology. 2016 Feb 9;86(6):505-11. [Abstract]
  • Auriel E, Charidimou A, Gurol ME, Ni J, Van Etten ES, Martinez-Ramirez S, Boulouis G, Piazza F, DiFrancesco JC, Frosch MP, Pontes-Neto OV, Shoamanesh A, Reijmer Y, Vashkevich A, Ayres AM, Schwab KM, Viswanathan A, Greenberg SM. Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation. JAMA Neurol. 2016 Feb 1;73(2):197-202. [Abstract]
  • van Veluw SJ, Biessels GJ, Bouvy WH, Spliet WG, Zwanenburg JJ, Luijten PR, Macklin EA, Rozemuller AJ, Gurol ME, Greenberg SM, Viswanathan A, Martinez-Ramirez S. Cerebral amyloid angiopathy severity is linked to dilation of juxtacortical perivascular spaces. J Cereb Blood Flow Metab. 2015 Dec 7. [Abstract]
  • Martinez-Ramirez S, Romero JR, Shoamanesh A, McKee AC, Van Etten E, Pontes-Neto O, Macklin EA, Ayres A, Auriel E, Himali JJ, Beiser AS, DeCarli C, Stein TD, Alvarez VE, Frosch MP, Rosand J, Greenberg SM, Gurol ME, Seshadri S, Viswanathan A. Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage. Alzheimers Dement. 2015 Dec;11(12):1480-8. [Abstract] [Full Article]
  • Zhao L, Arbel-Ornath M, Wang X, Betensky RA, Greenberg SM, Frosch MP, Bacskai BJ. Matrix metalloproteinase 9-mediated intracerebral hemorrhage induced by cerebral amyloid angiopathy. Neurobiol Aging. 2015 Nov;36(11):2963-71. [Abstract] [Full Article]
  • Ni J, Auriel E, Jindal J, Ayres A, Schwab KM, Martinez-Ramirez S, Gurol EM, Greenberg SM, Viswanathan A. The characteristics of superficial siderosis and convexity subarachnoid hemorrhage and clinical relevance in suspected cerebral amyloid angiopathy. Cerebrovasc Dis. 2015;39(5-6):278-86. [Abstract] [Full Article]
  • Yan P, Zhu A, Liao F, Xiao Q, Kraft AW, Gonzales E, Perez R, Greenberg SM, Holtzman DM, Lee JM. Minocycline reduces spontaneous hemorrhage in mouse models of cerebral amyloid angiopathy. Stroke. 2015 Jun;46(6):1633-40. [Abstract] [Full Article]
  • Reijmer YD, Schultz AP, Leemans A, O'Sullivan MJ, Gurol ME, Sperling R, Greenberg SM, Viswanathan A, Hedden T. Decoupling of structural and functional brain connectivity in older adults with white matter hyperintensities. Neuroimage. 2015 May 27;117:222-229. [Abstract] [Full Article]
  • Boulouis G, Dumas A, Betensky RA, Brouwers HB, Fotiadis P, Vashkevich A, Ayres A, Schwab K, Romero JM, Smith EE, Viswanathan A, Goldstein JN, Rosand J, Gurol ME, Greenberg SM. Anatomic pattern of intracerebral hemorrhage expansion: relation to CT angiography spot sign and hematoma center. Stroke. 2014 Apr;45(4):1154-6. [Abstract] [Full Article]
  • Auriel E, Edlow BL, Reijmer YD, Fotiadis P, Ramirez-Martinez S, Ni J, Reed AK, Vashkevich A, Schwab K, Rosand J, Viswanathan A, Wu O, Gurol ME, Greenberg SM. Microinfarct disruption of white matter structure: a longitudinal diffusion tensor analysis. Neurology. 2014 Jul 8;83(2):182-8. [Abstract] [Full Article]
  • Thanprasertsuk S, Martinez-Ramirez S, Pontes-Neto OM, Ni J, Ayres A, Reed A, Swords K, Gurol ME, Greenberg SM, Viswanathan A. Posterior white matter disease distribution as a predictor of amyloid angiopathy. Neurology. 2014 Aug 26;83(9):794-800. [Abstract] [Full Article]
  • van Etten ES, Auriel E, Haley KE, Ayres AM, Vashkevich A, Schwab KM, Rosand J, Viswanathan A, Greenberg SM, Gurol ME. Incidence of symptomatic hemorrhage in patients with lobar microbleeds. Stroke. 2014 Aug;45(8):2280-5. [Abstract]
  • Shoamanesh A, Martinez-Ramirez S, Oliveira-Filho J, Reijmer Y, Falcone GJ, Ayres A, Schwab K, Goldstein JN, Rosand J, Gurol ME, Viswanathan A1, Greenberg SM. Interrelationship of superficial siderosis and microbleeds in cerebral amyloid angiopathy. Neurology. 2014 Nov 11;83(20):1838-43. [Abstract] [Full Article]
  • Reijmer YD, Fotiadis P, Martinez-Ramirez S, Salat DH, Schultz A, Shoamanesh A, Ayres AM, Vashkevich A, Rosas D, Schwab K, Leemans A, Biessels GJ, Rosand J, Johnson KA, Viswanathan A, Gurol ME, Greenberg SM. Structural network alterations and neurological dysfunction in cerebral amyloid angiopathy. Brain. 2015 Jan;138(Pt 1):179-88. [Abstract] [Full Article]
  • Charidimou A, Martinez-Ramirez S, Shoamanesh A, Jamary Oliveira-Filho J, Frosch M, Vashkevich A, Ayres A, Rosand J, Gurol ME, Greenberg SM, Viswanathan A. Cerebral amyloid angiopathy with and without hemorrhage: evidence for different disease phenotypes. Neurology. 2015 Mar 24;84(12):1206-12. [Abstract] [Full Article]
  • Brouwers HB, Chang Y, Falcone GJ, Cai X, Ayres AM, Battey TW, Vashkevich A, McNamara KA, Valant V, Schwab K, Orzell SC, Bresette LM, Feske SK, Rost NS, Romero JM, Viswanathan A, Chou SH, Greenberg SM, Rosand J, Goldstein JN. Predicting hematoma expansion after primary intracerebral hemorrhage. JAMA Neurol. 2014;71(2):158-64. [Abstract] [Full Article]
  • Rannikme K, Kalaria RN, Greenberg SM, Chui HC, Schmitt FA, Samarasekera N, Al-Shahi Salman R, Sudlow CL. APOE associations with severe CAA-associated vasculopathic changes: collaborative meta-analysis. J Neurol Neurosurg Psychiatry 2014;85(3):300-5.. [Abstract] [Full Article]
  • Arbel-Ornath M, Hudry E, Eikermann-Haerter K, Hou S, Gregory JL, Zhao L, Betensky RA, Frosch MP, Greenberg SM, Bacskai BJ. Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer's disease mouse models. Acta Neuropathol. 2013;126(3):353-64. [Abstract] [Full Article]
  • Piazza F, Greenberg SM, Savoiardo M, Gardinetti M, Chiapparini L, Raicher I, Nitrini R, Sakaguchi H, Brioschi M, Billo G, Colombo A, Lanzani F, Piscosquito G, Carriero MR, Giaccone G, Tagliavini F, Ferrarese C, Difrancesco JC. Anti-amyloid autoantibodies in cerebral amyloid angiopathy-related inflammation: Implications for Amyloid-Modifying Therapies. Ann Neurol 2013;73(4):449-58. [Abstract]
  • Martinez-Ramirez S, Pontes-Neto OM, Dumas AP, Auriel E, Halpin A, Quimby M, Gurol ME, Greenberg SM, Viswanathan A. Topography of dilated perivascular spaces in subjects from a memory clinic cohort. Neurology 2013;80:1551-6. [Abstract] [Full Article]
  • Gurol ME, Viswanathan A, Gidicsin C, Hedden T, Martinez-Ramirez S, Dumas A, Vashkevich A, Ayres AM, Auriel E, van Etten E, Becker A, Carmasin J, Schwab K, Rosand J, Johnson KA, Greenberg SM. Cerebral amyloid angiopathy burden associated with leukoaraiosis: A positron emission tomography/magnetic resonance imaging study. Ann Neurol 2013;73(4):529-36. [Abstract] [Full Article]
  • Greenberg CH, Frosch MP, Goldstein JN, Rosand J, Greenberg SM. Modeling intracerebral hemorrhage growth and response to anticoagulation. PLoS One 2012;7:e48458. [Abstract] [Full Article]
  • Auriel E, Gurol ME, Ayres A, Dumas AP, Schwab KM, Vashkevich A, Martinez-Ramirez S, Rosand J, Viswanathan A, Greenberg SM. Characteristic distributions of intracerebral hemorrhage-associated diffusion-weighted lesions. Neurology 2012;79:2335-41. [Abstract] [Full Article]
  • Gregory JL, Prada CM, Fine SJ, Garcia-Alloza M, Betensky RA, Arbel-Ornath M, Greenberg SM, Bacskai BJ, Frosch MP. Reducing available soluble -amyloid prevents progression of cerebral amyloid angiopathy in transgenic mice. J Neuropathol Exp Neurol 2012;71:1009-17. [Abstract] [Full Article]
  • Gurol ME, Dierksen G, Betensky R, Gidicsin C, Halpin A, Becker A, Carmasin J, Ayres A, Schwab K, Viswanathan A, Salat D, Rosand J, Johnson KA, Greenberg SM. Predicting sites of new hemorrhage with amyloid imaging in cerebral amyloid angiopathy. Neurology 2012;79:320-6. [Abstract] [Full Article]
  • Dumas A, Dierksen GA, Gurol ME, Halpin A, Martinez-Ramirez S, Schwab K, Rosand J, Viswanathan A, Salat DH, Polimeni JR, Greenberg SM. Functional magnetic resonance imaging detection of vascular reactivity in cerebral amyloid angiopathy. Ann Neurol 2012;72:76-81. [Abstract] [Full Article]
  • Biffi A, Shulman JM, Jagiella JM, Cortellini L, Ayres AM, Schwab K, Brown DL, Silliman SL, Selim M, Worrall BB, Meschia JF, Slowik A, De Jager PL, Greenberg SM, Schneider JA, Bennett DA, Rosand J. Genetic variation at CR1 increases risk of cerebral amyloid angiopathy. Neurology 2012;78:334-41. [Abstract] [Full Article]
  • Biffi A, Plourde A, Shen Y, Onofrio R, Smith EE, Frosch M, Prada CM, Gusella J, Greenberg SM, Rosand J. Screening for familial APP mutations in sporadic cerebral amyloid angiopathy. PLoS One 2010;5:e13949.[Abstract] [Full Article]
  • Dierksen GA, Skehan ME, Khan MA, Jeng J, Nandigam RN, Becker JA, Kumar A, Neal KL, Betensky RA, Frosch MP, Rosand J, Johnson KA, Viswanathan A, Salat DH, Greenberg SM. Spatial relation between microbleeds and amyloid deposits in amyloid angiopathy. Ann Neurol 2010;68:545-8. [Abstract] [Full Article]
  • Biffi A, Halpin A, Towfighi A, Gilson A, Busl K, Rost N, Smith EE, Greenberg MS, Rosand J, Viswanathan A. Aspirin and recurrent intracerebral hemorrhage in cerebral amyloid angiopathy. Neurology 2010;75:693-698. [Abstract] [Full Article]
  • Linn J, Halpin A, Demaerel P, Ruhland J, Giese AD, Dichgans M, van Buchem MA, Bruckmann H, Greenberg SM. Prevalence of superficial siderosis in patients with cerebral amyloid angiopathy. Neurology 2010;74:1346-1350. [Abstract] [Full Article]
  • Tomidokoro Y, Rostagno A, Neubert TA, Lu Y, Rebeck GW, Frangione B, Greenberg SM, Ghiso J. Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AD23N in parenchymal and cerebrovascular amyloid deposits. Am J Pathol 2010;176:1841-1854. [Abstract] [Full Article]
  • Verbeek MM, Kremer BP, Olde Rikkert M, van Domburg PH, Skehan ME, Greenberg SM. Cerebrospinal fluid amyloid 40 is decreased in cerebral amyloid angiopathy. Ann Neurol 2009;66:245-9. [Abstract] [Full Article]
  • van Rooden S, van der Grond J, van den Boom R, Haan J, Linn J, Greenberg SM, van Buchem MA. Descriptive analysis of the Boston criteria applied to a Dutch-type cerebral amyloid angiopathy population. Stroke 2009;40:3022-7. [Abstract] [Full Article]
  • Garcia-Alloza M, Prada C, Lattarulo C, Fine S, Borrelli LA, Betensky R, Greenberg SM, Frosch MP, Bacskai BJ. Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice. J Neurochem 2009;109:1636-47. [Abstract] [Full Article]
  • Kimberly WT, Gilson A, Rost NS, Rosand J, Viswanathan A, Smith EE, Greenberg SM. Silent ischemic infarcts are associated with hemorrhage burden in cerebral amyloid angiopathy. Neurology 2009;72:1230-1235. [Abstract] [Full Article]
  • Viswanathan A, Raj S, Greenberg SM, Stampfer M, Campbell S, Hyman BT, Irizarry MC. Plasma A, homocysteine, and cognition: the Vitamin Intervention for Stroke Prevention (VISP) trial. Neurology 2009;72:268-272. [Abstract] [Full Article]
  • Viswanathan A, Patel P, Rahman R, Nandigam RN, Kinnecom C, Bracoud L, Rosand J, Chabriat H, Greenberg SM, Smith EE. Tissue microstructural changes are independently associated with cognitive impairment in cerebral amyloid angiopathy. Stroke 2008;39:1988-1992. [Abstract] [Full Article]
  • Greenberg SM, Grabowski TJ, Gurol ME, Skehan ME, Nandigam RNK, Becker JA, Garcia-Alloza M, Prada C, Frosch MP, Rosand J, Viswanathan A, Smith EE, Johnson KA. Detection of isolated cerebrovascular -amyloid with Pittsburgh compound B. Ann Neurol 2008;64:587-591. [Abstract] [Full Article]
  • Smith EE, Vijayappa M, Lima F, Delgado P, Wendell L, Rosand J, Greenberg SM. Impaired visual evoked flow response in cerebral amyloid angiopathy. Neurology 2008;71:1424-1430. [Abstract] [Full Article]
  • Nakagawa K, Sheikh SI, Snuderl M, Frosch MP, Greenberg, SM. A new Thr49Pro transthyretin gene mutation associated with leptomeningeal amyloidosis. J Neurol Sci 2008;272:186-190. [Abstract]
  • Holland CM, Smith EE, Csapo I, Gurol ME, Brylka DA, Killiany RJ, Blacker D, Albert MS, Guttmann CRG, Greenberg SM. Spatial distribution of white matter hyperintensities in Alzheimer's disease, cerebral amyloid angiopathy, and healthy aging. Stroke 2008;39:1127-1133. [Abstract] [Full Article]
  • Shin HK, Jones PB, Garcia-Alloza M, Borrelli L, Greenberg SM, Bacskai BJ, Frosch MP, Hyman BT, Moskowitz MA, Ayata C. Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy. Brain 2007;130:2310-2319. [Abstract] [Full Article]
  • Johnson KA, Gregas M, Becker JA, Kinnecom C, Salat DH, Moran EK, Smith EE, Rosand J, Rentz DM, Klunk WE, Mathis CA, Price JC, DeKosky ST, Fischman AJ, Greenberg SM. Imaging of amyloid burden and distribution in cerebral amyloid angiopathy. Ann Neurol 2007;62:229-234. [Abstract]
  • Kinnecom C, Lev MH, Wendell L, Smith EE, Rosand J, Frosch MP, Greenberg SM. Course of cerebral amyloid angiopathy-related inflammation. Neurology 2007;68;1411-1416. [Abstract]
  • Prada C, Garcia-Alloza M, Zhang-Nunes SX, Betensky RA, Greenberg SM, Bacskai BJ, Frosch MP. Antibody-mediated clearance of A from cerebral amyloid angiopathy revealed by quantitative in vivo imaging. J Neurosci 2007;27:1973-1980. [Abstract] [Full Article]
  • Bacskai BJ, Frosch MP, Freeman SH, Raymond SB, Augustinack JC, Johnson KA, Irizarry MC, Klunk WE, Mathis CA, Dekosky ST, Greenberg SM, Hyman BT, Growdon JH. Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report. Arch Neurol 2007;64:431-434. [Abstract]
  • Greenberg SM, Rosand J, Schneider AT, Pettigrew LC, Gandy SE, Rovner B, Fitzsimmons B-F, Smith EE, Gurol ME, Schwab K, Laurin J, Garceau D. A phase II study of tramiprosate for cerebral amyloid angiopathy. Alzheimer Dis Assoc Disord 2006;20:269-274. [Abstract]
  • Salat DH, Smith ES, Tuch DS, Benner T, Pappu V, Schwab KM, Gurol ME, Rosas HD, Rosand J, Greenberg SM. White matter alterations in cerebral amyloid angiopathy measured by diffusion tensor imaging. Stroke 2006;37:1759-1764. [Abstract] [Full Article]
  • Garcia-Alloza M, Robbins EM, Zhang-Nunes SX, Purcell SM, Betensky RA, Raju S, Prada C, Greenberg SM, Bacskai BJ, Frosch MP. Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease. Neurobiol Dis 2006;24:516-524. [Abstract]
  • Guo S, Wang S, Kim WJ, Lee SR, Frosch MP, Bacskai BJ, Greenberg SM, Lo EH. Effects of apoE isoforms on beta-amyloid-induced matrix metalloproteinase-9 in rat astrocytes. Brain Res 2006;1111:222-226. [Abstract]
  • Chen Y-W, Gurol ME, Rosand J, Viswanathan A, Rakich SM, Groover TR, Greenberg SM, Smith EE. Progression of white matter lesions and hemorrhages in cerebral amyloid angiopathy. Neurology 2006:67:83-87. [Abstract] [Full Article]
  • Gurol ME, Irizarry MC, Smith EE, Raju S, Diaz-Arrastia R, Bottiglieri T, Rosand J, Growdon JH, Greenberg SM. Plasma -amyloid and white matter lesions in AD, MCI, and cerebral amyloid angiopathy. Neurology 2006;66:23-29. [Abstract]
  • Robbins EM, Betensky RA, Domnitz SB, Purcell SM, Garcia-Alloza M, Greenberg C, Rebeck GW, Hyman BT, Greenberg SM, Frosch MP, Bacskai BJ. Kinetics of cerebral amyloid angiopathy progression in a transgenic mouse model of Alzheimer disease. J Neurosci 2006;26:365-371. [Abstract]
  • Irizarry MC, Gurol ME, Raju S, Diaz-Arrastia R, Locascio JJ, Tennis M, Hyman BT, Growdon JH, Greenberg SM, Bottiglieri T. Association of homocysteine with plasma amyloid protein in aging and neurodegenerative disease. Neurology 2005;65:1402-1408. [Abstract]
  • Rosand J, Muzikansky A, Kumar A, Wisco JJ, Smith EE, Betensky RA, Greenberg SM. Spatial clustering of hemorrhages in probable cerebral amyloid angiopathy. Ann Neurol 2005;58:459-462. [Abstract]
  • Domnitz SB, Robbins EM, Hoang AW, Garcia-Alloza M, Hyman BT, Rebeck GW, Greenberg SM, Bacskai BJ, Frosch MP. Progression of cerebral amyloid angiopathy in transgenic mouse models of Alzheimer disease. J Neuropathol Exp Neurol 2005;64:588-594. [Abstract]
  • Smith EE, Gurol ME, Eng JA, Engel CR, Nguyen TN, Rosand J, Greenberg SM. White matter lesions, cognition, and recurrent hemorrhage in lobar hemorrhage. Neurology 2004;63:1606-1612. [Abstract]
  • Greenberg SM, Eng JA, Ning MM, Smith EE, Rosand J. Hemorrhage burden predicts recurrent intracerebral hemorrhage following lobar hemorrhage. Stroke 2004;35:1415-1420. [Abstract]
  • Eng JA, Frosch MP, Choi K, Rebeck GW, Greenberg SM. Clinical manifestations of cerebral amyloid angiopathy-related inflammation. Ann Neurol 2004;55:246-252. [Abstract]
  • Greenberg SM, Shin Y, Grabowski TJ, Cooper GE, Rebeck GW, Iglesias S, Chapon F, Tournier-Lasserve E, Baron J-C. Hemorrhagic stroke associated with the Iowa amyloid precursor protein mutation. Neurology 2003;60:1020-1022. [Abstract]
  • Shin Y, Cho HS, Fukumoto H, Shimizu T, Shirasawa T, Greenberg SM, Rebeck GW. A species, including IsoAsp23 A, in Iowa-type familial cerebral amyloid angiopathy. Acta Neuropathologica 2003;105:252. [Abstract]
  • Van Nostrand WE, Melchor JP, Cho HS, Greenberg SM, Rebeck GW. Pathogenic effects of D23N 'Iowa' mutant amyloid -protein. J Biol Chem 2001;276:32860-32866. [Abstract]
  • Grabowski TJ, Cho HS, Vonsattel JPG, Rebeck GW, Greenberg SM. A novel APP mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy. Ann Neurol 2001;49:697-705. [Abstract]
  • Knudsen KA, Rosand J, Karluk D, Greenberg SM. Clinical diagnosis of cerebral amyloid angiopathy. Validation of the Boston criteria. Neurology 2001;56:537-539. [Abstract]
  • Cho HS, Hyman BT, Greenberg SM, Rebeck GW. Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in A aggregation. J Neuropathol Exp Neurol 2001;60:342-349. [Abstract]
  • Rosand J, Hylek EM, O'Donnell HC, Greenberg SM. Warfarin-related hemorrhage and cerebral amyloid angiopathy. A genetic and pathological study. Neurology 2000;55:947-955. [Abstract]
  • O'Donnell HC, Rosand J, Knudsen KA, Furie KL, Segal AZ, Chiu RI, Ikeda D, Greenberg SM. Apolipoprotein E genotype and risk of recurrent lobar intracerebal hemorrhage. New Engl J Med, 2000;342:240-245. [Abstract]
  • Greenberg SM, O'Donnell HC, Schaefer PW, Kraft, E. MRI detection of new hemorrhages. Potential marker of progression in cerebral amyloid angiopathy. Neurology 1999;53:1135-1138. [Abstract]
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Full List of Reviews, Chapters, Editorials

  • Boulouis G, Charidimou A, Van Veluw S, Greenberg SM. Imaging the Acute Formation of a Cortical Microbleed in Cerebral Amyloid Angiopathy. JAMA Neurol. 2017 Jan 1;74(1):120-121. [Abstract]
  • Reijmer YD, van Veluw SJ, Greenberg SM. Ischemic brain injury in cerebral amyloid angiopathy. J Cereb Blood Flow Metab. 2015 May 6. [Abstract]
  • Greenberg SM, Al-Shahi Salman R, Biessels GJ, van Buchem M, Cordonnier C, Lee JM, Montaner J, Schneider JA, Smith EE, Vernooij M, Werring DJ. Outcome markers for clinical trials in cerebral amyloid angiopathy. Lancet Neurol. 2014 Apr;13(4):419-28. [Abstract] [Full Article]
  • Gurol ME, Greenberg SM. A physiologic biomarker for cerebral amyloid angiopathy. Neurology 2013;81(19):1650-1 [Abstract]
  • Auriel E, Greenberg SM. The pathophysiology and clinical presentation of cerebral amyloid angiopathy. Curr Atheroscler Rep 2012;14:343-50. [Abstract]
  • Smith EE, Schneider JA, Wardlaw JM, Greenberg SM. Cerebral microinfarcts: the invisible lesions. Lancet Neurol 2012;11:272-82. [Abstract] [Full Article]
  • Viswanathan A, Greenberg SM. Cerebral amyloid angiopathy in the elderly. Ann Neurol 2011;70:871-80. [Abstract] [Full Article]
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