Pathways to a Cure: The CAA Newsletter

Educational Materials

CAA Presentation

CAA Presentation
developed by the MGH Stroke Research Center

CAA Fact Sheet

CAA Fact Sheet
developed by the MGH Stroke Research Center

Book Recommendations

My Stroke of Insight Cover

My Stroke of Insight: A Brain Scientist's Personal Journey

Jill Bolte Taylor, Ph.D.

When Dr. Taylor suffered from a hemorrhagic stroke at the age of 37, she had the unique perspective of being a trained neuroanatomist. In this moving memoir, she recounts her experience of losing the ability to speak, walk, read and write - and her subsequent recovery - with the knowledge of a brain scientist. Although CAA was not the cause of her hemorrhage, her story of hope and recovery can be of great value to our patients and their caregivers. - Alison Ayres, Data Manager

The Brain That Changes Itself Cover

The Brain That Changes Itself: Stories of Personal Triumph from the Frontiers of Brain Science

Norman Doidge, M.D.

Dr. Doidge presents the extraordinary idea that our brains are not hard wired or fixed; our brains are incredibly plastic and the structure of our brain changes in response to our thoughts. Doidge explores the extent of our brains' malleability and the power of neurorehabilitation. He presents the case of a man who recovers from a devastating stroke, a woman who thrives despite being born with half of a brain, and several other moving stories of the brain's ability to heal. I recommend this book to anyone who would like to understand and be inspired by the incredible resilience of our brains. - Anne Reed, Clinical Research Coordinator

Harvard Medical School Guide to Achieving Optimal Memory Cover

Harvard Medical School Guide to Achieving Optimal Memory

Aaron Nelson, Ph.D., M.D.

Dr. Nelson's study offers good insights into differences between cognitive changes associated with normal aging and changes due to different disease processes. A good book to help patients and family understand the mechanisms of cognitive impairment in the elderly. The book also offers suggestions and potential approaches in daily life on how to improve one's memory. - Dr. Anand Viswanathan


International CAA Research Organizations

Online References

Medscape Reference

Cerebral Amyloid Angiopathy
by Ravi S Menon, MD for Medscape Emedicine

Up To Date

Cerebral Amyloid Angiopathy
by Steven M Greenberg, MD, PhD for Up To Date

Medlink Neurology

Cerebral Amyloid Angiopathy
by Steven M Greenberg, MD, PhD for MedLink Neurology
Select "Clinical Summaries" and enter search term "Cerebral Amyloid Angiopathy"


Cerebral Amyloid Angiopathy Facebook Page
managed by the MGH Stroke Research Center

Stroke of Insight TED Talk

'My Stroke of Insight' TED Talk
by stroke survivor and neuroanatomist Jill Bolte Taylor

In the News

Vascular Disease and Dementia cover

Vascular Disease and Dememtia
by Anand Viswanthan, M.D., Ph.D., Keep in Mind!; Fall/ Winter 2012
Article is on Page 6

MRI scan with microbleeds

A Quandary on Blood Drops in the Brain
by Gina Kolata, New York Times; July 1, 2008

Featured Original Articles

  • Fotiadis P, van Rooden S, van der Grond J, Schultz A, Martinez-Ramirez S, Auriel E, Reijmer Y, van Opstal AM, Ayres A, Schwab KM, Alzheimer's Disease Neuroimaging Initiative Adni, Hedden T, Rosand J, Viswanathan A, Wermer M, Terwindt GM, Sperling RA, Polimeni JR, Johnson KA, van Buchem MA, Greenberg SM, Gurol ME. Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study. Lancet Neurol. 2016 Jul;15(8):811-9. [Abstract] [Full Article]
  • Gurol ME, Becker JA, Fotiadis P, Riley G, Schwab K, Johnson KA, Greenberg SM. Florbetapir-PET to diagnose cerebral amyloid angiopathy: A prospective study. Neurology. 2016 Nov 8;87(19):2043-2049. [Abstract] [Full Article]
  • van Opstal AM, van Rooden S, van Harten T, Ghariq E, Labadie G, Fotiadis P, Gurol ME, Terwindt GM, Wermer MJ, van Buchem MA, Greenberg SM, van der Grond J. Cerebrovascular function in presymptomatic and symptomatic individuals with hereditary cerebral amyloid angiopathy: a case-control study. Lancet Neurol. 2017 Feb;16(2):115-122. [Abstract]
  • Auriel E, Charidimou A, Gurol ME, Ni J, Van Etten ES, Martinez-Ramirez S, Boulouis G, Piazza F, DiFrancesco JC, Frosch MP, Pontes-Neto OV, Shoamanesh A, Reijmer Y, Vashkevich A, Ayres AM, Schwab KM, Viswanathan A, Greenberg SM. Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation. JAMA Neurol. 2016 Feb 1;73(2):197-202. [Abstract]
  • Martinez-Ramirez S, Romero JR, Shoamanesh A, McKee AC, Van Etten E, Pontes-Neto O, Macklin EA, Ayres A, Auriel E, Himali JJ, Beiser AS, DeCarli C, Stein TD, Alvarez VE, Frosch MP, Rosand J, Greenberg SM, Gurol ME, Seshadri S, Viswanathan A. Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage. Alzheimers Dement. 2015 Dec;11(12):1480-8. [Abstract] [Full Article]
  • Reijmer YD, Fotiadis P, Martinez-Ramirez S, Salat DH, Schultz A, Shoamanesh A, Ayres AM, Vashkevich A, Rosas D, Schwab K, Leemans A, Biessels GJ, Rosand J, Johnson KA, Viswanathan A, Gurol ME, Greenberg SM. Structural network alterations and neurological dysfunction in cerebral amyloid angiopathy. Brain. 2015 Jan;138(Pt 1):179-88. [Abstract] [Full Article]
  • Arbel-Ornath M, Hudry E, Eikermann-Haerter K, Hou S, Gregory JL, Zhao L, Betensky RA, Frosch MP, Greenberg SM, Bacskai BJ. Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer's disease mouse models. Acta Neuropathol. 2013;126(3):353-64. [Abstract] [Full Article]
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Featured Reviews, Chapters, Editorials

  • Greenberg SM, Al-Shahi Salman R, Biessels GJ, van Buchem M, Cordonnier C, Lee JM, Montaner J, Schneider JA, Smith EE, Vernooij M, Werring DJ. Outcome markers for clinical trials in cerebral amyloid angiopathy. Lancet Neurol. 2014 Apr;13(4):419-28. [Abstract] [Full Article]
  • Smith EE, Schneider JA, Wardlaw JM, Greenberg SM. Cerebral microinfarcts: the invisible lesions. Lancet Neurol 2012;11:272-82. [Abstract] [Full Article]
  • Viswanathan A, Greenberg SM. Cerebral amyloid angiopathy in the elderly. Ann Neurol 2011;70:871-80. [Abstract]
  • Greenberg SM, Vernooij MW, Cordonnier C, Viswanathan A, Al-Shahi Salman R, Warach S, Launer LJ, Van Buchem MA, Breteler MM; Microbleed Study Group. Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol 2009;8:165-74. [Abstract] [Full Article]
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